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Role of Diffusion Tensor Imaging and Motor Functional MRI in Preoperative Assessment of Brain Tumors

Received: 20 December 2020     Accepted: 30 December 2020     Published: 12 January 2021
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Abstract

Diffusion tensor imaging is a non-invasive magnetic resonance imaging technique that describe the orientation and location of white matter tracts in vivo, it guides the surgeon regarding the relationship of the intra-axial tumor to adjacent white matter tracts in different planes. Routine pre-surgical FMRI allows for assessment of the relationship between brain tumor and motor cortex to facilitate function-preserving surgery and reduce postoperative morbidity. The purpose of this study is to evaluate role of diffusion tensor magnetic resonance imaging, fiber tractography and motor functional MRI in assessment of white matter tracts affected by the tumor, and to utilize this information in guiding surgeons. Fifty patients with different types of brain tumors were enrolled in this study. Fiber tracts involvement were classified into four categories (edema, displacement, infiltration and disruption), comparison between benign and malignant tumors groups as regards to the patterns of fiber tracts involvement were done. The prevalence of edema and displacement was higher among the benign group while prevalence of infiltration and disruption was higher among the malignant group. Localization of the primary motor hand area with functional MRI was done, The relation of it to the tumor was measured. Treatment plans before and after DTI & functional MR imaging differed in 35 patients as regard to surgical approach and in 17 patients as regard to modification of extent of resection with significant relation. Diffusion tensor imaging DTI represents recent important progress in the field of diagnostic imaging. It is the only technique that is able to visualize in vivo white-matter tracts so that it is of great help in pre-operative neurosurgical planning.

Published in International Journal of Medical Imaging (Volume 9, Issue 1)
DOI 10.11648/j.ijmi.20210901.12
Page(s) 16-28
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Diffusion Tensor Imaging, Fiber Tractography, Motor Functional MRI, Brain Tumors

References
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    Sara Essam Hasby, Al-Shaimaa Zakaria Elshahawy, Mohamed Amin Mohamed, Ali Ibraheem Seif Eldean, Mohammed Fathy Dawoud. (2021). Role of Diffusion Tensor Imaging and Motor Functional MRI in Preoperative Assessment of Brain Tumors. International Journal of Medical Imaging, 9(1), 16-28. https://doi.org/10.11648/j.ijmi.20210901.12

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    ACS Style

    Sara Essam Hasby; Al-Shaimaa Zakaria Elshahawy; Mohamed Amin Mohamed; Ali Ibraheem Seif Eldean; Mohammed Fathy Dawoud. Role of Diffusion Tensor Imaging and Motor Functional MRI in Preoperative Assessment of Brain Tumors. Int. J. Med. Imaging 2021, 9(1), 16-28. doi: 10.11648/j.ijmi.20210901.12

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    AMA Style

    Sara Essam Hasby, Al-Shaimaa Zakaria Elshahawy, Mohamed Amin Mohamed, Ali Ibraheem Seif Eldean, Mohammed Fathy Dawoud. Role of Diffusion Tensor Imaging and Motor Functional MRI in Preoperative Assessment of Brain Tumors. Int J Med Imaging. 2021;9(1):16-28. doi: 10.11648/j.ijmi.20210901.12

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  • @article{10.11648/j.ijmi.20210901.12,
      author = {Sara Essam Hasby and Al-Shaimaa Zakaria Elshahawy and Mohamed Amin Mohamed and Ali Ibraheem Seif Eldean and Mohammed Fathy Dawoud},
      title = {Role of Diffusion Tensor Imaging and Motor Functional MRI in Preoperative Assessment of Brain Tumors},
      journal = {International Journal of Medical Imaging},
      volume = {9},
      number = {1},
      pages = {16-28},
      doi = {10.11648/j.ijmi.20210901.12},
      url = {https://doi.org/10.11648/j.ijmi.20210901.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20210901.12},
      abstract = {Diffusion tensor imaging is a non-invasive magnetic resonance imaging technique that describe the orientation and location of white matter tracts in vivo, it guides the surgeon regarding the relationship of the intra-axial tumor to adjacent white matter tracts in different planes. Routine pre-surgical FMRI allows for assessment of the relationship between brain tumor and motor cortex to facilitate function-preserving surgery and reduce postoperative morbidity. The purpose of this study is to evaluate role of diffusion tensor magnetic resonance imaging, fiber tractography and motor functional MRI in assessment of white matter tracts affected by the tumor, and to utilize this information in guiding surgeons. Fifty patients with different types of brain tumors were enrolled in this study. Fiber tracts involvement were classified into four categories (edema, displacement, infiltration and disruption), comparison between benign and malignant tumors groups as regards to the patterns of fiber tracts involvement were done. The prevalence of edema and displacement was higher among the benign group while prevalence of infiltration and disruption was higher among the malignant group. Localization of the primary motor hand area with functional MRI was done, The relation of it to the tumor was measured. Treatment plans before and after DTI & functional MR imaging differed in 35 patients as regard to surgical approach and in 17 patients as regard to modification of extent of resection with significant relation. Diffusion tensor imaging DTI represents recent important progress in the field of diagnostic imaging. It is the only technique that is able to visualize in vivo white-matter tracts so that it is of great help in pre-operative neurosurgical planning.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - Role of Diffusion Tensor Imaging and Motor Functional MRI in Preoperative Assessment of Brain Tumors
    AU  - Sara Essam Hasby
    AU  - Al-Shaimaa Zakaria Elshahawy
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    AB  - Diffusion tensor imaging is a non-invasive magnetic resonance imaging technique that describe the orientation and location of white matter tracts in vivo, it guides the surgeon regarding the relationship of the intra-axial tumor to adjacent white matter tracts in different planes. Routine pre-surgical FMRI allows for assessment of the relationship between brain tumor and motor cortex to facilitate function-preserving surgery and reduce postoperative morbidity. The purpose of this study is to evaluate role of diffusion tensor magnetic resonance imaging, fiber tractography and motor functional MRI in assessment of white matter tracts affected by the tumor, and to utilize this information in guiding surgeons. Fifty patients with different types of brain tumors were enrolled in this study. Fiber tracts involvement were classified into four categories (edema, displacement, infiltration and disruption), comparison between benign and malignant tumors groups as regards to the patterns of fiber tracts involvement were done. The prevalence of edema and displacement was higher among the benign group while prevalence of infiltration and disruption was higher among the malignant group. Localization of the primary motor hand area with functional MRI was done, The relation of it to the tumor was measured. Treatment plans before and after DTI & functional MR imaging differed in 35 patients as regard to surgical approach and in 17 patients as regard to modification of extent of resection with significant relation. Diffusion tensor imaging DTI represents recent important progress in the field of diagnostic imaging. It is the only technique that is able to visualize in vivo white-matter tracts so that it is of great help in pre-operative neurosurgical planning.
    VL  - 9
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Author Information
  • Department of Radiology, Faculty of Medicine, Tanta University, Tanta, Egypt

  • Department of Radiology, Faculty of Medicine, Tanta University, Tanta, Egypt

  • Department of Radiology, Faculty of Medicine, Tanta University, Tanta, Egypt

  • Department of Neurosurgery, Faculty of Medicine, Tanta University, Tanta, Egypt

  • Department of Radiology, Faculty of Medicine, Tanta University, Tanta, Egypt

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