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Outcome of RT-PCR in the Diagnosis of Patients with COVID-19 Symptoms: A Study in a COVID-19 Referral Hospital

Received: 2 November 2023     Accepted: 27 November 2023     Published: 24 May 2024
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Abstract

Introduction: Corona virus (SARS-CoV-2) (COVID-19) outbreak was first reported in China rapidly spread around the world within short period causing global public health emergency. COVID 19 is a highly infectious disease caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2). The initial symptoms were fever, cough, dyspnea, myalgia or fatigue, headache, hemoptysis, diarrhea and acute respiratory distress syndrome (ARDS). Hence in diagnosis of COVID-19 RT-PCR of viral nucleic acid is regarded as the reference standard to detect the COVID-19 positive cases. Objective: The aim of this study was to determine the outcome of RT-PCR of the patients with COVID-19 symptoms. Methodology: This was a cross-sectional prospective study carried out in the department of Radiology and imaging in collaboration with the department of Virology and COVID unit in IbnSina Hospital, Dhaka, Bangladesh during January, 2022 to June, 2022. A total of 239 OPD patients with COVID-19 symptoms aged above 18 years were enrolled in this study. The collected data were cleaned, edited and entered into computer for analysis. The data were analyzed using Statistical Package for Social Sciences (SPSS) software, version 23.0. The ethical clearance of this study was obtained from the Ethics Committee of School of Public Health & Life Science, University of South Asia, and Dhaka, Bangladesh. Results: In this study a total of (n=239) patients with COVID-19 symptoms were enrolled. According to age distribution, the majority., 142 (59.42%) patients belonged to the age group >52 years, which was the highest and followed by 44 (18.42%) age group (43-52) years, 36 (15.06%) (33-42) years, 14 (5.85%) (22-32) years and 3 (1.25%) <22 years. According to sex distribution, the majority, 167 (69.85%) were male and 72 (30.12%) were female. Distribution by symptoms, all the patients239 (100%) had general weakness and followed by sneezing 221 (92.46%), fever 236 (98.74%), headache 228 (95.39%), cough 232 (97.07%), respiratory distress, 225 (94.14%), cough and SOB, 237 (99.16%), loss of smell, 212 (88.74%), lac of apatite, 224 (73.72%), asthma 218 (91.21%) and pneumonia, 118 (49.37%). In RT_PCR lab test results, the majority 195 (81.58%) were observed COVID-19 Negative (-) and 44 (18.41%) were observed COVID-19 Positive (+). Among the positive cases, the majority 26 (60%) were male and 18 (40%) were female. Conclusion: This study prevailed around 20 % of the patients with COVID-19 symptoms got COVID-19 Positive in RT-PCR lab test results. Therefore, the patients with COVID-19 symptoms must conduct RT-PCR lab test for their being sure of their COVID-19 affection. At the same time, the male are more vulnerable to COVID-19 than their counter part female.

Published in International Journal of Medical Imaging (Volume 12, Issue 2)
DOI 10.11648/j.ijmi.20241202.16
Page(s) 57-61
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Outcome, RT-PCR, COVID-19, Symptoms Referral

References
[1] Zhu N, Zhang D, Wang W, et al. A novel coronavirus from patients with pneumonia in China, 2019. New Engl J Med 2020; 382: 727-33. [PMC free article] [PubMed] [Google Scholar]
[2] Wang C, Horby PW, Hayden FG, et al. A novel coronavirus outbreak of global health concern. Lancet 2020; 395: 470-3. [PMC free article] [PubMed] [Google Scholar]
[3] Lu H, Stratton CW, Tang YW. Outbreak of pneumonia of unknown etiology in Wuhan China: the mystery and the miracle. J Med Virol 2020; 92: 401-2. [PMC free article] [PubMed] [Google Scholar]
[4] Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020; 395: 497-506. [PMC free article] [PubMed] [Google Scholar]
[5] Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet 2020; 395: 507-13. [PMC free article] [PubMed] [Google Scholar]
[6] Sohrabi C, Alsafi Z, O’Neill N, et al. World Health Organization declares global emergency: A review of the 2019 novel coronavirus (COVID-19). Inter J Surg 2020; 76: 71-6. [Google Scholar]
[7] Institute of Epidemiology Disease Control and Research (IEDCR). Bangladesh Covid-19 update. 2020. Available from:
[8] Maswood MH. Young, working-age people mostly infected with COVID-19 in Bangladesh. 2020. Available from:
[9] Worldometer. COVID19 Coronaviruspandemic. 2020. Available from:
[10] Anwar S, Nasrullah M, Hossen MJ. COVID-19 and Bangladesh: challenges and how to address them. Front Pub Healt 2020; 8154. [PMC free article] [PubMed] [Google Scholar]
[11] Lorenzo GD, Rossella DT. Coronavirus disease (covid-19) in Italy: analysis of risk factors and proposed remedial measures. Front Med 2020; 7: 140. [PMC free article] [PubMed] [Google Scholar]
[12] Nasir N, Habib K, Khanum I. Clinical characteristics and outcomes of COVID-19: experience at a major tertiary care center in Pakistan. J Infect Dev Ctries 2021; 15: 480–9.
[13] CA, Haritha D, Soni L, et al. Epidemiological & clinical characteristics & early outcome of COVID-19 patients in a tertiary.
[14] Saha A, Ahsan MM, Quader MT-U, et al. Clinical characteristics and outcomes of COVID-19 infected diabetic patients admitted in ICUs of the southern region of Bangladesh. Diabetes Metab Syndr 2021; 15: 229–35.
[15] Md S M, Mosabbir AA, Chowdhury P. Clinical manifestations of patients with coronavirus disease 2019 (COVID-19) attending at hospitals in Bangladesh. Infectious Diseases 2020.
[16] Ali MR, Hasan MA, Rahman MS, et al. Clinical manifestations and socio-demographic status of COVID-19 patients during the secondwave of pandemic: a Bangladeshi experience. J Infect Public Health 2021; 14: 1367–74.
[17] Mahmud R, Rahman MM, Rassel MA, et al. Post-COVID-19 syndrome among symptomatic COVID-19 patients: a prospective cohort study in a tertiary care center of Bangladesh. PLoS One 2021; 16: e0249644.
[18] Li L-Q, Huang T, Wang Y-Q, et al. COVID-19 patients' clinical characteristics, discharge rate, and fatality rate of meta-analysis. J Med Virol 2020; 92: 577–83.
[19] Moura DTHde, Proença IM, McCarty TR, et al. Gastrointestinal manifestations and associated health outcomes of COVID-19: a Brazilian experience from the largest South American public hospital. Clinics 2020; 75: e2271.
[20] Ai Tang Xiao, Yi Xin Tong, Sheng Zhang, Profile of RT-PCR for SARS-CoV-2: A Preliminary Study From 56 COVID-19 Patients, Clinical Infectious Diseases, Volume 71, Issue 16, 15 October 2020, Pages 2249–2251,
[21]
[22] ARDS Definition Task Force, Ranieri VM, Rubenfeld GD, et al. Acute respiratory distress syndrome: the Berlin definition. JAMA 2012; 307: 2526–33.
[23] Kayina CA, Haritha D, Soni L, et al. Epidemiological & clinical characteristics & early outcome of COVID-19 patients in a tertiarycare teaching hospital in India: A preliminary analysis. Indian J Med Res 2020; 152: 100–4.
Cite This Article
  • APA Style

    Rahman, M. M., Akanda, A. R., Rahman, M. M., Abedin, M. S., Sumon, S. R., et al. (2024). Outcome of RT-PCR in the Diagnosis of Patients with COVID-19 Symptoms: A Study in a COVID-19 Referral Hospital. International Journal of Medical Imaging, 12(2), 57-61. https://doi.org/10.11648/j.ijmi.20241202.16

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    ACS Style

    Rahman, M. M.; Akanda, A. R.; Rahman, M. M.; Abedin, M. S.; Sumon, S. R., et al. Outcome of RT-PCR in the Diagnosis of Patients with COVID-19 Symptoms: A Study in a COVID-19 Referral Hospital. Int. J. Med. Imaging 2024, 12(2), 57-61. doi: 10.11648/j.ijmi.20241202.16

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    AMA Style

    Rahman MM, Akanda AR, Rahman MM, Abedin MS, Sumon SR, et al. Outcome of RT-PCR in the Diagnosis of Patients with COVID-19 Symptoms: A Study in a COVID-19 Referral Hospital. Int J Med Imaging. 2024;12(2):57-61. doi: 10.11648/j.ijmi.20241202.16

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  • @article{10.11648/j.ijmi.20241202.16,
      author = {Mohammad Mojibur Rahman and Abdur Rab Akanda and Mohammad Motiur Rahman and Mohammad Salehin Abedin and Sohel Rana Sumon and Mohammad Ripon Sikder and Marzuk Ahamed},
      title = {Outcome of RT-PCR in the Diagnosis of Patients with COVID-19 Symptoms: A Study in a COVID-19 Referral Hospital
    },
      journal = {International Journal of Medical Imaging},
      volume = {12},
      number = {2},
      pages = {57-61},
      doi = {10.11648/j.ijmi.20241202.16},
      url = {https://doi.org/10.11648/j.ijmi.20241202.16},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20241202.16},
      abstract = {Introduction: Corona virus (SARS-CoV-2) (COVID-19) outbreak was first reported in China rapidly spread around the world within short period causing global public health emergency. COVID 19 is a highly infectious disease caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2). The initial symptoms were fever, cough, dyspnea, myalgia or fatigue, headache, hemoptysis, diarrhea and acute respiratory distress syndrome (ARDS). Hence in diagnosis of COVID-19 RT-PCR of viral nucleic acid is regarded as the reference standard to detect the COVID-19 positive cases. Objective: The aim of this study was to determine the outcome of RT-PCR of the patients with COVID-19 symptoms. Methodology: This was a cross-sectional prospective study carried out in the department of Radiology and imaging in collaboration with the department of Virology and COVID unit in IbnSina Hospital, Dhaka, Bangladesh during January, 2022 to June, 2022. A total of 239 OPD patients with COVID-19 symptoms aged above 18 years were enrolled in this study. The collected data were cleaned, edited and entered into computer for analysis. The data were analyzed using Statistical Package for Social Sciences (SPSS) software, version 23.0. The ethical clearance of this study was obtained from the Ethics Committee of School of Public Health & Life Science, University of South Asia, and Dhaka, Bangladesh. Results: In this study a total of (n=239) patients with COVID-19 symptoms were enrolled. According to age distribution, the majority., 142 (59.42%) patients belonged to the age group >52 years, which was the highest and followed by 44 (18.42%) age group (43-52) years, 36 (15.06%) (33-42) years, 14 (5.85%) (22-32) years and 3 (1.25%) Conclusion: This study prevailed around 20 % of the patients with COVID-19 symptoms got COVID-19 Positive in RT-PCR lab test results. Therefore, the patients with COVID-19 symptoms must conduct RT-PCR lab test for their being sure of their COVID-19 affection. At the same time, the male are more vulnerable to COVID-19 than their counter part female.
    },
     year = {2024}
    }
    

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  • TY  - JOUR
    T1  - Outcome of RT-PCR in the Diagnosis of Patients with COVID-19 Symptoms: A Study in a COVID-19 Referral Hospital
    
    AU  - Mohammad Mojibur Rahman
    AU  - Abdur Rab Akanda
    AU  - Mohammad Motiur Rahman
    AU  - Mohammad Salehin Abedin
    AU  - Sohel Rana Sumon
    AU  - Mohammad Ripon Sikder
    AU  - Marzuk Ahamed
    Y1  - 2024/05/24
    PY  - 2024
    N1  - https://doi.org/10.11648/j.ijmi.20241202.16
    DO  - 10.11648/j.ijmi.20241202.16
    T2  - International Journal of Medical Imaging
    JF  - International Journal of Medical Imaging
    JO  - International Journal of Medical Imaging
    SP  - 57
    EP  - 61
    PB  - Science Publishing Group
    SN  - 2330-832X
    UR  - https://doi.org/10.11648/j.ijmi.20241202.16
    AB  - Introduction: Corona virus (SARS-CoV-2) (COVID-19) outbreak was first reported in China rapidly spread around the world within short period causing global public health emergency. COVID 19 is a highly infectious disease caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2). The initial symptoms were fever, cough, dyspnea, myalgia or fatigue, headache, hemoptysis, diarrhea and acute respiratory distress syndrome (ARDS). Hence in diagnosis of COVID-19 RT-PCR of viral nucleic acid is regarded as the reference standard to detect the COVID-19 positive cases. Objective: The aim of this study was to determine the outcome of RT-PCR of the patients with COVID-19 symptoms. Methodology: This was a cross-sectional prospective study carried out in the department of Radiology and imaging in collaboration with the department of Virology and COVID unit in IbnSina Hospital, Dhaka, Bangladesh during January, 2022 to June, 2022. A total of 239 OPD patients with COVID-19 symptoms aged above 18 years were enrolled in this study. The collected data were cleaned, edited and entered into computer for analysis. The data were analyzed using Statistical Package for Social Sciences (SPSS) software, version 23.0. The ethical clearance of this study was obtained from the Ethics Committee of School of Public Health & Life Science, University of South Asia, and Dhaka, Bangladesh. Results: In this study a total of (n=239) patients with COVID-19 symptoms were enrolled. According to age distribution, the majority., 142 (59.42%) patients belonged to the age group >52 years, which was the highest and followed by 44 (18.42%) age group (43-52) years, 36 (15.06%) (33-42) years, 14 (5.85%) (22-32) years and 3 (1.25%) Conclusion: This study prevailed around 20 % of the patients with COVID-19 symptoms got COVID-19 Positive in RT-PCR lab test results. Therefore, the patients with COVID-19 symptoms must conduct RT-PCR lab test for their being sure of their COVID-19 affection. At the same time, the male are more vulnerable to COVID-19 than their counter part female.
    
    VL  - 12
    IS  - 2
    ER  - 

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Author Information
  • Department of Public Health and Life Science, University of South Asia, Dhaka, Bangladesh

  • Department of Public Health and Life Science, University of South Asia, Dhaka, Bangladesh

  • Department of Public Health and Life Science, University of South Asia, Dhaka, Bangladesh

  • Department of Public Health and Life Science, University of South Asia, Dhaka, Bangladesh

  • Department of Public Health and Life Science, University of South Asia, Dhaka, Bangladesh

  • Department of Public Health and Life Science, University of South Asia, Dhaka, Bangladesh

  • Department of Public Health and Life Science, University of South Asia, Dhaka, Bangladesh

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